Fertile Window: When Are You Most Likely to Conceive?
If you're trying to get pregnant, understanding your fertile window is one of the most important things you can do to increase your chances of conception. Your fertile window is the limited time each menstrual cycle when pregnancy is possible -- and knowing exactly when this window occurs can make all the difference in your journey to parenthood.
Many couples are surprised to learn that there are only about six days per cycle when conception can occur. This comprehensive guide will explain everything you need to know about your fertile window: how long it lasts, how to identify it, which days have the highest conception rates, the science of sperm survival, evidence-based intercourse timing strategies, and what happens during the two-week wait after ovulation.
Quick Summary
- Your fertile window is approximately 6 days per cycle
- It includes the 5 days before ovulation and ovulation day itself
- Peak fertility is the day before ovulation (33% conception rate)
- Having intercourse every 1-2 days during the fertile window maximizes chances
- Sperm can survive up to 5 days; the egg lives only 12-24 hours
- Implantation typically occurs 6-12 days past ovulation (DPO)
Table of Contents
- What Is the Fertile Window?
- The Science Behind Conception Timing
- The Science of Sperm Survival
- Conception Rates by Day
- How to Identify Your Fertile Window
- Cervical Mucus and Fertility
- Timing Intercourse for Conception
- Intercourse Frequency Studies: What the Research Says
- Intercourse Frequency and Conception Rates
- Sperm Survival Science
- Lubricants and Fertility
- The Two-Week Wait: From Ovulation to Pregnancy Test
- The Two-Week Wait Day-by-Day Timeline
- Common Mistakes to Avoid
- Frequently Asked Questions
What Is the Fertile Window?
The fertile window is the period during your menstrual cycle when sexual intercourse can result in pregnancy. This window exists because of the limited lifespans of both sperm and eggs. While sperm can survive in the female reproductive tract for up to five days under optimal conditions, an egg is only viable for fertilization for approximately 12 to 24 hours after ovulation.
These biological constraints create a window of fertility that spans about six days: the five days leading up to ovulation (when sperm can be waiting for the egg) and the day of ovulation itself (when the egg is available for fertilization). After ovulation day, the egg quickly becomes non-viable, and pregnancy from that cycle becomes impossible regardless of intercourse timing.
Why Is the Fertile Window So Short?
The short duration of the fertile window is determined by basic reproductive biology:
- Egg viability: Once released from the ovary, an egg must be fertilized within 12-24 hours before it degenerates
- Sperm survival: While sperm can survive up to 5 days in fertile cervical mucus, their fertilization capacity decreases over time
- Travel time: Sperm need time to travel through the cervix, uterus, and into the fallopian tube where fertilization occurs
This means that for conception to occur, sperm must either already be present in the reproductive tract when ovulation happens, or arrive within hours of the egg's release. Having sperm "waiting" for the egg (by having intercourse before ovulation) is generally more effective than trying to time intercourse for the exact moment of ovulation.
When Does the Fertile Window Occur?
The timing of your fertile window depends on when you ovulate, which is determined by your cycle length. For a typical 28-day cycle where ovulation occurs on day 14, the fertile window would be approximately days 9-14. Use our ovulation calculator to estimate your personal fertile window based on your cycle.
The table below shows how the fertile window shifts across different cycle lengths. Remember that ovulation typically occurs about 14 days before your next period -- so the luteal phase stays constant while the follicular phase (and thus the fertile window timing) shifts based on cycle length. For a deeper explanation of this timing, see our guide on how many days after your period you ovulate.
| Cycle Length | Estimated Ovulation Day | Fertile Window (Approx.) |
|---|---|---|
| 21 days | Day 7 | Days 2-7 |
| 24 days | Day 10 | Days 5-10 |
| 26 days | Day 12 | Days 7-12 |
| 28 days | Day 14 | Days 9-14 |
| 30 days | Day 16 | Days 11-16 |
| 32 days | Day 18 | Days 13-18 |
| 35 days | Day 21 | Days 16-21 |
| 40 days | Day 26 | Days 21-26 |
If your cycle is 21 days or shorter, your fertile window may overlap with your period. In a 21-day cycle, ovulation can occur as early as day 7 -- meaning sperm from intercourse during the later days of your period (days 2-5) could still be alive when the egg is released. This is one reason the American College of Obstetricians and Gynecologists (ACOG) cautions that calendar-based methods alone are not reliable contraception.
The Science Behind Conception Timing
To truly understand your fertile window, it helps to know what happens biologically during conception and why timing matters so much.
The Journey of Sperm
After ejaculation, sperm face a challenging journey through the female reproductive tract:
- Cervix: Sperm must first pass through the cervix. During the fertile window, cervical mucus becomes thin and stretchy, creating channels that help sperm swim through. Outside the fertile window, mucus is thick and acts as a barrier.
- Uterus: Sperm swim through the uterus toward the fallopian tubes. This journey takes several hours.
- Fallopian tubes: Sperm must enter the correct fallopian tube (the one containing the egg) and undergo capacitation -- a process that prepares them for fertilization.
Of the millions of sperm released, only a few hundred typically reach the egg. This journey and preparation process takes time, which is why having sperm already present before ovulation increases conception chances. According to the American Society for Reproductive Medicine (ASRM), timed intercourse in the days leading up to ovulation provides the best odds.
Sperm Survival and Quality
While sperm can survive up to 5 days in the female reproductive tract, their fertilization capability changes over time:
- First 1-2 days: Sperm are highly motile and have peak fertilization capacity
- Days 3-4: Motility and fertilization capacity begin to decline
- Day 5: Only the hardiest sperm remain viable, with significantly reduced fertilization capacity
This declining capacity explains why intercourse closer to ovulation generally results in higher conception rates than intercourse five days before.
The Egg's Brief Window
Once ovulation occurs, the egg has a very limited time for fertilization. The egg is released from the ovary and captured by the fimbriae (finger-like projections) at the end of the fallopian tube. It then travels down the tube over 12-24 hours.
Fertilization typically occurs in the upper portion of the fallopian tube, within the first 12-24 hours after ovulation. If sperm don't reach the egg during this window, the egg begins to degenerate and can no longer be fertilized. For more on the physical signs that ovulation is occurring, see our dedicated guide.
The Science of Sperm Survival
Understanding how long sperm can survive -- and what factors influence that survival -- is essential for optimizing your conception strategy. Sperm survival in the female reproductive tract is not a simple yes-or-no matter; it depends on a complex interplay of biological factors.
Lifespan in the Female Reproductive Tract
Under ideal conditions, sperm can survive in the female reproductive tract for up to 5 days, though most studies suggest that 3 days is a more typical upper limit for maintaining meaningful fertilization capacity. A landmark study by Wilcox et al. (1995) demonstrated pregnancies resulting from intercourse up to 5 days before ovulation, confirming this extended survival range.
Outside the body -- on skin, on clothing, or exposed to air -- sperm die within minutes to hours. The warm, protective environment of the cervix and uterus is specifically what allows extended survival. Cervical crypts (small pocket-like structures in the cervical canal) serve as reservoirs where sperm can be stored and gradually released over several days.
The Role of Cervical Mucus in Sperm Survival
Fertile-quality cervical mucus is arguably the single most important factor in sperm survival. This egg-white-consistency mucus does several critical things:
- Nourishment: Fertile mucus contains sugars (fructose and glucose) that provide energy for sperm to swim and survive
- pH buffering: The vagina is naturally acidic (pH 3.8-4.5), which is hostile to sperm. Fertile cervical mucus has a pH of 7.0-8.5, neutralizing the acidic environment
- Transport channels: The molecular structure of fertile mucus creates parallel channels that guide sperm toward the uterus
- Filtration: Mucus filters out abnormal or poorly motile sperm, allowing only the healthiest to pass through
Without fertile-quality cervical mucus, sperm survival drops dramatically -- from days to mere hours. This is why the fertile window is functionally tied to the presence of this mucus, which typically appears 3-5 days before ovulation.
Sperm Capacitation
Before sperm can fertilize an egg, they must undergo a process called capacitation. This molecular change, which takes approximately 7-10 hours after ejaculation, involves:
- Removal of cholesterol from the sperm cell membrane
- Changes in calcium ion flow that create a hyperactive swimming pattern
- Preparation of the acrosome (the enzyme-containing cap on the sperm head) for the "acrosome reaction" needed to penetrate the egg
Capacitation is one reason why having sperm present before ovulation is beneficial -- they need time to become fully capable of fertilization. According to Mayo Clinic, this biological preparation time is a key reason the day before ovulation yields higher conception rates than ovulation day itself.
Factors Affecting Sperm Survival
| Factor | How It Affects Survival | What to Do |
|---|---|---|
| Cervical mucus quality | Fertile-quality mucus extends survival to 3-5 days; hostile mucus kills sperm within hours | Stay hydrated, consider mucinex (guaifenesin) to thin mucus, track CM patterns |
| Vaginal pH | Acidic environment (pH below 6) is toxic to sperm; optimal is pH 7.0-8.5 | Avoid douching and scented products that disrupt natural pH balance |
| Timing relative to ovulation | Mucus quality peaks 1-2 days before ovulation, providing the best survival conditions | Use OPKs and CM tracking to identify peak fertility |
| Lubricant use | Most commercial lubricants are spermicidal, reducing motility by 60-100% | Use fertility-friendly lubricants (Pre-Seed) or rely on natural lubrication |
| Sperm health | Higher initial quality means more sperm survive the journey and remain viable longer | Maintain healthy lifestyle, avoid heat exposure, limit alcohol |
| Infections or inflammation | Cervical or vaginal infections create hostile conditions that reduce survival | Treat any infections before attempting conception |
- Sperm can survive up to 5 days, but 2-3 days with strong fertilization capacity is more typical
- Fertile cervical mucus is the critical enabler of extended sperm survival
- Sperm need 7-10 hours to undergo capacitation before they can fertilize an egg
- Having intercourse 1-2 days before ovulation gives sperm the best combination of survival time and readiness
Conception Rates by Day
Research has established that conception rates vary significantly depending on which day of the fertile window intercourse occurs. The most widely cited data comes from the landmark Wilcox et al. (1995) study published in the New England Journal of Medicine, which tracked 221 women prospectively to establish day-specific conception probabilities.
Daily Conception Probabilities
Based on multiple large-scale studies, here are the approximate chances of conception from a single act of intercourse on each day relative to ovulation:
| Day Relative to Ovulation | Conception Rate | Fertility Level |
|---|---|---|
| 5 days before ovulation (O-5) | ~5% | Low |
| 4 days before ovulation (O-4) | ~10% | Low-Moderate |
| 3 days before ovulation (O-3) | ~15% | Moderate |
| 2 days before ovulation (O-2) | ~25% | High |
| 1 day before ovulation (O-1) | ~33% | Peak |
| Ovulation day (O) | ~8% | Moderate (declining) |
| 1 day after ovulation (O+1) | ~0% | Very Low / None |
| 2+ days after ovulation | 0% | None |
Why the Day Before Ovulation Is Peak
The day before ovulation has the highest conception rate (approximately 33%) for several reasons:
- Sperm have time to complete their journey and capacitation process
- Fresh, highly motile sperm are ready and waiting when the egg is released
- Cervical mucus is at peak fertility quality
- There's no risk of "missing" ovulation by being too late
The relatively low rate on ovulation day itself (~8%) may surprise many people. This occurs because by ovulation day, the window for sperm to travel and capacitate is narrowing rapidly, and the egg's viability is limited to just 12-24 hours. The Stanford et al. (2002) review confirmed these findings across multiple population studies.
Cumulative Probability
If you have intercourse on multiple days during your fertile window, your overall chances of conception increase. A healthy couple having regular intercourse during the fertile window has approximately a 20-30% chance of conceiving in any given cycle. Over 6 months of trying, about 80% of couples will conceive; after 12 months, about 90%. If you've been trying for 12 months without success (or 6 months if over 35), it may be time to see a fertility specialist.
How to Identify Your Fertile Window
There are several methods you can use to identify your fertile window, ranging from simple calendar tracking to more precise physiological indicators.
Calendar Method
The simplest approach is to estimate your fertile window based on your cycle length. Since ovulation typically occurs 14 days before your next period, you can calculate backwards:
- Track your cycles for several months to determine your average length
- Subtract 14 from your cycle length to estimate ovulation day
- Your fertile window begins 5 days before that estimated ovulation day
Our ovulation calculator does this math for you and provides a visual calendar of your fertile days.
Ovulation Predictor Kits (OPKs)
Ovulation predictor kits detect the surge in luteinizing hormone (LH) that occurs 24-36 hours before ovulation. This gives you advance notice that ovulation is imminent, allowing you to time intercourse optimally. Tips for using OPKs:
- Begin testing a few days before you expect to ovulate
- Test in the afternoon when LH levels are typically highest
- A positive result means you should have intercourse that day and the next
- Continue testing until you see a clear negative after the positive
Basal Body Temperature (BBT)
Your basal body temperature rises by about 0.5-1 degrees F after ovulation due to progesterone. While BBT tracking can confirm that ovulation has occurred, it can't predict it in advance. However, tracking over several cycles can help you identify patterns and predict future ovulation timing. According to the NHS, combining BBT with other methods provides the most complete fertility picture.
Fertility Monitors
Digital fertility monitors provide more comprehensive tracking by measuring multiple hormones (estrogen and LH) or combining multiple fertility indicators. These devices can give you a wider warning of approaching fertility and confirm when ovulation has occurred.
Cervical Mucus and Fertility
Cervical mucus is one of the most reliable indicators of your fertile window, and learning to recognize its changes can significantly improve your ability to identify your most fertile days.
How Cervical Mucus Changes Through Your Cycle
Your cervical mucus changes in response to estrogen levels, becoming progressively more fertile as ovulation approaches:
| Phase | Mucus Characteristics | Fertility Status |
|---|---|---|
| After period | Dry or very little mucus | Not fertile |
| Early follicular | Sticky, tacky, white or yellowish | Low fertility |
| Mid-follicular | Creamy, lotion-like, white | Transitional |
| Approaching ovulation | Wet, slippery, clear, stretchy (like egg whites) | High fertility |
| After ovulation | Sticky or dry again | Not fertile |
Egg White Cervical Mucus (EWCM)
The most fertile type of cervical mucus is often called "egg white cervical mucus" because of its resemblance to raw egg whites. This mucus:
- Is clear or slightly cloudy
- Is stretchy -- can stretch an inch or more between fingers without breaking
- Feels slippery and lubricative
- Creates an ideal environment for sperm survival and transport
When you observe EWCM, you are likely in your fertile window and approaching ovulation. This is an excellent time for intercourse if you're trying to conceive. A 2004 study by Bigelow et al. published in Human Reproduction found that cervical mucus observations were actually a better predictor of conception than timing of intercourse alone.
How to Check Cervical Mucus
You can check your cervical mucus by:
- Observing mucus on toilet paper after wiping
- Checking mucus directly at the cervix with clean fingers
- Noting the sensation throughout the day (wet/slippery vs. dry)
Check once or twice daily, at the same times if possible. Record your observations to identify patterns over multiple cycles.
Timing Intercourse for Conception
Once you've identified your fertile window, the next question is how often to have intercourse to maximize your chances of conception.
Recommended Frequency
Research suggests that having intercourse every 1-2 days during your fertile window provides the best balance between sperm quality and ensuring sperm are present when ovulation occurs. Specifically:
- Every day: Maximizes chances that sperm are present, but may slightly reduce sperm count per ejaculation
- Every other day: Allows sperm count to rebuild while still maintaining good coverage of the fertile window
- Every 2-3 days throughout the month: A "don't miss it" approach that works even if ovulation timing varies
The "Don't Save It Up" Myth
Some couples believe they should abstain from intercourse before the fertile window to "save up" sperm. However, research shows that frequent ejaculation does not significantly reduce fertility. In fact, sperm that sit in the reproductive tract for too long can have reduced motility and increased DNA damage. Regular ejaculation (every 2-3 days) actually helps maintain sperm quality.
Optimal Timing Strategy
Based on research, an effective strategy is:
- Begin having intercourse every 1-2 days starting about 5-6 days before expected ovulation
- When you see fertile cervical mucus or a positive OPK, have intercourse that day and the next
- Continue through the day after confirmed ovulation (via BBT rise or OPK turning negative)
Position and Other Factors
There's no scientific evidence that any particular sexual position increases conception chances. Sperm are deposited near the cervix during ejaculation and quickly enter the cervical mucus. Lying down after intercourse for 10-15 minutes may help, though evidence is limited. The most important factor is timing, not position.
Intercourse Frequency Studies: What the Research Says
One of the most common questions couples have when trying to conceive is how often they should have intercourse. Fortunately, several well-designed studies have examined this question directly.
Daily vs. Every-Other-Day: The Research
The ASRM committee opinion (2017) on optimizing natural fertility reviewed the evidence and concluded that daily and every-other-day intercourse during the fertile window produce nearly identical pregnancy rates. Here is what the data shows:
- Daily intercourse during the fertile window: ~37% cycle fecundity (chance of pregnancy per cycle)
- Every-other-day intercourse during the fertile window: ~33% cycle fecundity
- Once per week: ~15% cycle fecundity
The difference between daily and every-other-day is not statistically significant, meaning either approach is effective. The Wilcox data further showed that the critical factor is not how many times you have intercourse, but whether at least one act falls within the 3-day peak window (O-3 to O-1).
The Stanford Data
A comprehensive review by Stanford et al. (2002) in Obstetrics & Gynecology analyzed data from multiple large studies and confirmed that:
- Peak fertility is concentrated in a 3-day window ending on ovulation day
- Having intercourse on at least 2-3 days during the fertile window is nearly as effective as having intercourse every day
- The probability of pregnancy is near zero if intercourse occurs only after ovulation
The Sperm Meets Egg Plan (SMEP)
The SMEP is a popular evidence-based protocol that many fertility communities recommend. It was designed to balance intercourse frequency with practical lifestyle considerations:
- Starting on cycle day 8: Have intercourse every other day
- Begin OPK testing on cycle day 10 (adjust based on your typical cycle length)
- When you get a positive OPK: Have intercourse that night, the next night, and skip one night, then one more time
- After ovulation is confirmed: Resume normal activity
The SMEP ensures that fresh sperm are present in the reproductive tract at all times during the fertile window, while the intensification around the positive OPK targets the peak conception days. Many couples find this structured approach reduces anxiety about "missing" the window.
Multiple Ejaculations and Sperm Quality
A concern for many couples is whether frequent ejaculation depletes sperm quality. Research addresses this directly:
- Sperm concentration: Decreases modestly (by about 20-30%) with daily ejaculation compared to every-other-day, but total motile sperm count remains well above the threshold needed for conception
- Sperm DNA integrity: Actually improves with more frequent ejaculation. Sperm that sit in the epididymis for extended periods accumulate reactive oxygen species (ROS) damage
- Abstinence beyond 5 days: Associated with declining sperm quality, not improvement
- Optimal abstinence interval: 2-3 days maximizes total motile sperm count with good DNA integrity
- Every day or every other day during the fertile window -- both work equally well
- Don't "save up" sperm by abstaining; regular ejaculation maintains quality
- The SMEP provides a structured approach if you prefer a protocol
- Covering at least the 3-day peak window (O-3 to O-1) is more important than total frequency
- For men with low sperm counts, every-other-day may be slightly preferable to daily
Intercourse Frequency and Conception Rates
Beyond knowing when to have intercourse, understanding how often makes a measurable difference in conception rates. A key ASRM committee opinion (2017) analyzed multiple population-level datasets to quantify the relationship between intercourse frequency during the fertile window and per-cycle pregnancy rates.
Conception Rates by Intercourse Frequency
The following chart summarizes per-cycle conception rates based on how frequently couples had intercourse during the fertile window. These figures are drawn from studies of healthy couples with no known fertility issues.
| Intercourse Frequency | Per-Cycle Conception Rate | Key Consideration |
|---|---|---|
| Daily during fertile window | ~37% | Highest rate; sperm concentration slightly lower per ejaculation but total motile count remains adequate |
| Every other day during fertile window | ~33% | Nearly identical to daily; allows sperm count recovery between acts; less pressure on couples |
| Twice per week (throughout cycle) | ~20% | Reasonable rate if timing is not precisely tracked; may miss peak days in some cycles |
| Once per week | ~15% | Significantly lower; high chance of missing the peak 3-day window entirely |
The critical takeaway is that the difference between daily and every-other-day intercourse is not statistically significant. The Stanford et al. (2002) review confirmed that what matters most is ensuring at least one act of intercourse falls within the 3-day peak window (O-3 through O-1). Couples who have intercourse only once per week have roughly half the conception rate of those who have intercourse every other day, largely because they are more likely to miss the peak window entirely.
For couples using fertility tracking methods such as OPKs or cervical mucus monitoring, even twice-per-week intercourse can approach the higher rates if it is timed to coincide with the identified fertile window.
If you are actively tracking your cycle, aim for intercourse every 1-2 days during the fertile window. If you are not tracking, intercourse every 2-3 days throughout the entire cycle ensures you will likely cover the fertile window in most cycles. There is no need to have intercourse more than once per day, as it does not improve conception rates and can increase stress.
Sperm Survival Science
Sperm survival in the female reproductive tract is not a fixed number -- it varies dramatically depending on the hormonal environment, the quality of cervical mucus, and the health of the sperm themselves. Understanding these nuances can help you time intercourse more effectively and recognize why certain days in your fertile window carry higher conception odds than others.
Sperm Lifespan in Fertile vs. Hostile Mucus
The single most important factor determining how long sperm survive inside the reproductive tract is the type of cervical mucus present. According to Mayo Clinic, fertile-quality mucus creates a hospitable environment that extends sperm survival from hours to days.
In fertile cervical mucus (clear, stretchy, egg-white consistency), sperm can survive up to 5 days. The mucus provides nourishment through fructose and glucose, buffers the naturally acidic vaginal pH to a sperm-friendly 7.0-8.5, and creates channel-like structures that guide sperm toward the fallopian tubes. Cervical crypts act as sperm reservoirs, slowly releasing viable sperm over several days.
In hostile or non-fertile mucus (thick, sticky, scant, or absent), sperm are exposed to the vagina's low pH (3.8-4.5) without protection. In this environment, most sperm lose motility within 1-2 hours and die within 4-6 hours. This stark difference underscores why the fertile window is tightly linked to the presence of fertile cervical mucus, which typically appears 3-5 days before ovulation.
Sperm Viability Timeline
The following table shows how sperm viability and fertilization capacity change over time after ejaculation, assuming the sperm have entered fertile cervical mucus.
| Time After Ejaculation | Sperm Viability | Fertilization Capacity | Notes |
|---|---|---|---|
| 0-6 hours | High (~95% motile) | Undergoing capacitation | Sperm are traveling and preparing; not yet fully capable of fertilization |
| 6-12 hours | High (~90% motile) | Peak (capacitation complete) | Sperm have completed capacitation and are at maximum fertilization readiness |
| 12-24 hours | High (~80% motile) | Peak | Optimal window where fresh, capacitated sperm meet a newly released egg |
| 24-48 hours (Day 1-2) | Moderate (~60% motile) | Strong | Still highly effective; most pregnancies from pre-ovulation intercourse are within this range |
| 48-72 hours (Day 2-3) | Moderate (~40% motile) | Moderate | Declining but still viable; stored sperm being released from cervical crypts |
| 72-96 hours (Day 3-4) | Low (~20% motile) | Low | Significantly reduced numbers; only the hardiest sperm remain |
| 96-120 hours (Day 4-5) | Very low (~5-10% motile) | Very low | Rare but documented pregnancies from intercourse at O-5; maximum documented survival |
Factors That Shorten or Extend Sperm Survival
Several factors can influence whether sperm survive closer to the minimum or maximum of the 1-5 day range:
- Cervical mucus quality: The presence of egg-white cervical mucus is the primary enabler of extended survival. Women who produce abundant fertile mucus give sperm the best chance of surviving multiple days.
- Sperm health: Men with higher initial sperm motility and lower DNA fragmentation produce sperm that survive longer. Lifestyle factors such as diet, exercise, avoiding excessive heat, and limiting alcohol all contribute to sperm resilience.
- Vaginal microbiome: A healthy vaginal microbiome dominated by Lactobacillus species supports normal pH regulation. Bacterial vaginosis or yeast infections can create a more hostile environment for sperm.
- Hydration: Adequate hydration supports the production of fertile-quality cervical mucus. Some women find that taking guaifenesin (the active ingredient in Mucinex) can thin cervical mucus, though clinical evidence for this approach is limited.
- Lubricant use: As discussed in the lubricants and fertility section, most commercial lubricants are harmful to sperm and can dramatically shorten their lifespan.
For a comprehensive understanding of how to track the cervical mucus changes that signal sperm-friendly conditions, see our guide on cervical mucus and fertility.
Lubricants and Fertility
Many couples trying to conceive are unaware that common personal lubricants can significantly impair sperm function. A study published in Fertility and Sterility found that several popular lubricants reduced sperm motility by 60-100% in laboratory settings. The American Society for Reproductive Medicine (ASRM) recommends that couples trying to conceive either avoid lubricants or use fertility-friendly alternatives.
How Lubricants Affect Sperm
Lubricants can harm sperm through several mechanisms:
- Osmolality: Many lubricants are hyperosmotic (higher solute concentration than body fluids), which draws water out of sperm cells, causing them to shrink and lose motility
- pH imbalance: Some lubricants have a pH that is too acidic for sperm survival, similar to the naturally acidic vaginal environment
- Chemical additives: Preservatives, parabens, and glycerin in some lubricants can be directly toxic to sperm
- Viscosity: Thick lubricants can physically impede sperm movement through the cervical canal
Lubricant Comparison for Fertility
The following table compares common lubricant types and their effects on sperm, based on published research.
| Lubricant Type | Effect on Sperm | Recommendation |
|---|---|---|
| Water-based (e.g., KY Jelly, Astroglide) | Reduces motility by 60-100%; hyperosmotic formulations draw water from sperm cells; may contain spermicidal additives | Avoid when trying to conceive |
| Silicone-based (e.g., Uberlube, Wet Platinum) | Less studied than water-based; some evidence of moderate motility reduction (20-40%); does not mix with body fluids as readily | Avoid when trying to conceive; insufficient safety data for fertility use |
| Pre-Seed (fertility-friendly) | Designed to mimic fertile cervical mucus; iso-osmotic formulation; FDA-cleared as fertility-compatible; minimal impact on motility in studies | Recommended if lubrication is needed; apply intravaginally per instructions for best results |
| Coconut oil | Limited studies suggest minimal negative impact on sperm motility; natural antimicrobial properties may affect vaginal flora; not pH-matched to reproductive tract | Acceptable alternative if Pre-Seed is unavailable; not compatible with latex condoms |
| Saliva | Reduces motility by 20-30%; contains digestive enzymes that can damage sperm; hypotonic (lower solute concentration causes sperm to swell and burst) | Avoid as a lubricant when trying to conceive; use only for foreplay away from the vaginal area |
What to Use Instead
If you need lubrication during intercourse while trying to conceive, consider these fertility-safe approaches:
- Pre-Seed: The most studied fertility-friendly lubricant, specifically formulated to match the pH and osmolality of fertile cervical mucus. Apply a small amount intravaginally using the provided applicator.
- Mineral oil or canola oil: Studies have shown these do not impair sperm motility. They are inexpensive and widely available, though not specifically designed for reproductive use.
- Extended foreplay: Allowing more time for natural arousal can increase natural lubrication, reducing the need for added products.
- Hydration: Drinking plenty of water supports the body's production of natural cervical and vaginal fluids.
If vaginal dryness is persistent and significantly impacts intercourse, consult your healthcare provider. Chronic dryness can be caused by hormonal imbalances, medications (including some antihistamines and antidepressants), or underlying conditions that may also affect fertility. A doctor can evaluate whether treatment for dryness might also address related fertility concerns. The American College of Obstetricians and Gynecologists (ACOG) provides additional guidance on vulvovaginal health.
The Two-Week Wait: From Ovulation to Pregnancy Test
After ovulation and potential fertilization, there is an approximately 14-day period -- commonly called the "two-week wait" (TWW) -- before you can reliably test for pregnancy. Understanding what happens during this time can help manage expectations and reduce anxiety.
DPO Timeline: What Happens Day by Day
Here is what occurs in the days past ovulation (DPO) if fertilization was successful:
The Implantation Window (6-12 DPO)
Implantation is the critical step where the developing embryo establishes contact with the uterine lining. Research published in the New England Journal of Medicine (Wilcox et al., 1999) established the timing of implantation:
- 6 DPO: Earliest possible implantation (~0.5% of pregnancies)
- 7 DPO: ~3% of pregnancies implant
- 8 DPO: ~18% of pregnancies implant
- 9 DPO: ~36% of pregnancies implant (most common day)
- 10 DPO: ~27% of pregnancies implant
- 11 DPO: ~10% of pregnancies implant
- 12 DPO: ~5% of pregnancies implant (latest typical implantation)
Later implantation (after 11 DPO) is associated with a higher risk of early pregnancy loss, which is why most healthy pregnancies implant between 8-10 DPO.
When to Take a Pregnancy Test
The timing of your pregnancy test matters enormously for accuracy:
- 10 DPO: Some sensitive tests (detecting 10-15 mIU/mL hCG) may show a faint positive if implantation occurred early. However, a negative result at this point does not rule out pregnancy.
- 12 DPO: More reliable, especially with sensitive tests. About 50-60% of pregnancies will show a positive.
- 14 DPO (day of expected period): The most reliable timing. Approximately 95%+ of pregnancies will be detectable.
- After missed period: If your period is late and the test is still negative, retest in 2-3 days or request a blood hCG test from your doctor.
For detailed information on calculating timing after this stage, see our due date calculator from ovulation.
Early Pregnancy Symptoms vs. PMS
One of the most frustrating aspects of the two-week wait is that early pregnancy symptoms and premenstrual symptoms (PMS) are nearly identical. Both are caused by rising progesterone levels after ovulation. Common overlapping symptoms include:
- Breast tenderness and swelling
- Bloating and mild cramping
- Fatigue and mood changes
- Increased urination
- Food cravings or aversions
The only way to confirm pregnancy is through a positive pregnancy test (hCG detection). Symptom-spotting during the TWW, while understandable, is not diagnostically reliable. The Mayo Clinic notes that many early pregnancy symptoms don't become distinguishable from PMS until several weeks after the missed period.
hCG Doubling Times
If you receive a positive test, your doctor may order serial blood hCG tests to monitor early pregnancy viability. Normal hCG doubling times are:
- hCG below 1,200 mIU/mL: Doubles approximately every 48-72 hours
- hCG 1,200-6,000 mIU/mL: Doubles approximately every 72-96 hours
- hCG above 6,000 mIU/mL: Doubling slows further; peaks around 8-11 weeks
A slower-than-expected rise does not always indicate a problem, but a declining hCG level typically suggests a non-viable pregnancy. Your healthcare provider can interpret these results in the context of your individual situation.
The Two-Week Wait Day-by-Day Timeline
The period between ovulation and your expected period -- the two-week wait (TWW) -- can feel agonizingly slow. Knowing exactly what is happening biologically during each phase can help set realistic expectations about symptoms and testing. For a comprehensive overview of early pregnancy signs, the Cleveland Clinic provides an excellent resource.
Day-by-Day Implantation Timeline
If fertilization was successful, here is what happens during each phase of the two-week wait, along with what you may or may not feel.
| DPO (Days Past Ovulation) | Biological Event | Possible Symptoms | Can You Test? |
|---|---|---|---|
| 1 DPO | Fertilized egg (zygote) begins first cell division in the fallopian tube | None attributable to pregnancy; progesterone rising from corpus luteum | No -- far too early |
| 2 DPO | Zygote divides to 4 cells; still traveling down fallopian tube | None from pregnancy; possible mild ovulation-related cramping lingering | No |
| 3 DPO | Morula stage (8-16 cells); continues traveling toward uterus | None from pregnancy | No |
| 4 DPO | Morula enters uterine cavity; begins transforming into blastocyst | None from pregnancy; progesterone may cause breast tenderness or bloating (identical to PMS) | No |
| 5 DPO | Blastocyst (70-100 cells) floats freely in uterine cavity; hatches from zona pellucida | None from pregnancy | No |
| 6-7 DPO | Blastocyst begins attaching to uterine lining (earliest possible implantation; ~3% of pregnancies) | Rare: very faint cramping or spotting in a small minority of women | No -- even if implantation begins, hCG is not yet detectable |
| 8-9 DPO | Peak implantation window (~54% of pregnancies implant during this period); hCG production begins | Possible light spotting (implantation bleeding); mild cramping; some women report a "dip" in BBT | Possibly with very sensitive tests (10 mIU/mL); high false-negative rate |
| 10-11 DPO | hCG rising rapidly; doubling every 48-72 hours; implantation completing for most pregnancies | Breast tenderness increasing; possible fatigue, mild nausea; similar to PMS | Early tests may show faint positive; negative does not rule out pregnancy |
| 12-13 DPO | hCG levels typically 25-100 mIU/mL; placental development underway | Symptoms may intensify: breast changes, fatigue, frequent urination | Most standard tests will detect pregnancy; ~80-90% accuracy |
| 14 DPO | Expected period date for 28-day cycle; hCG typically 50-200+ mIU/mL if pregnant | Missed period is the most reliable sign; ongoing breast tenderness, fatigue | Yes -- reliable result with first morning urine; 95%+ accuracy |
Managing the Two-Week Wait
The TWW is often described as one of the most emotionally challenging parts of trying to conceive. The overlap between early pregnancy symptoms and premenstrual symptoms (both driven by progesterone) means that symptom-spotting is unreliable. Here are evidence-based strategies to cope:
- Stay occupied: Plan activities, projects, or social engagements to keep your mind engaged during the wait
- Limit internet symptom-searching: Research shows that excessive online searching during the TWW increases anxiety without improving outcomes
- Set a test date and stick to it: Decide in advance to test at 12 or 14 DPO, and avoid the temptation to test earlier, which increases the chance of ambiguous or false-negative results
- Maintain healthy habits: Continue exercising moderately, eating well, and taking prenatal vitamins as if you are pregnant
- Lean on support: Whether it is a partner, friend, or online community, sharing the experience can reduce isolation and stress
If anxiety during the TWW becomes overwhelming or you find that trying to conceive is significantly impacting your mental health, consider speaking with a therapist who specializes in fertility-related stress. Organizations like RESOLVE: The National Infertility Association offer support resources. For more on understanding what your body is going through during this period, our article on menstrual cycle phases provides helpful context about the luteal phase.
- Earliest meaningful test: 10 DPO with a sensitive test (high false-negative rate)
- Reasonably reliable: 12 DPO (most pregnancies detectable)
- Most reliable: 14 DPO / day of expected period (95%+ accuracy)
- If negative at 14 DPO: Pregnancy from this cycle is very unlikely; expect your period within 1-2 days
Common Mistakes to Avoid
When trying to conceive, there are several common misconceptions and mistakes that can reduce your chances of success.
Waiting for a Positive OPK Before Having Intercourse
A positive OPK means ovulation will occur in 24-36 hours. If you wait until you see a positive to start having intercourse, you're missing some of your most fertile days. Start having regular intercourse before you expect the positive result.
Only Having Intercourse on Ovulation Day
Many couples focus exclusively on "ovulation day," but the day before ovulation actually has higher conception rates. Additionally, if you miscalculate ovulation day by even one day, you could miss your window entirely. Covering multiple days is much more effective.
Assuming Day 14 Is Ovulation Day
Day 14 is only accurate for women with a 28-day cycle. If your cycles are shorter or longer, your ovulation day will differ. Always calculate based on YOUR cycle length, not the textbook 28-day cycle. See the fertile window by cycle length table above for guidance.
Becoming Stressed About Timing
Ironically, stress about conception timing can actually delay ovulation and reduce fertility. While timing is important, try to approach the fertile window with a relaxed attitude. Having regular intercourse throughout your cycle (every 2-3 days) is a low-stress approach that still covers your fertile window.
Ignoring Male Factor
Fertility is a two-person equation. While this article focuses on female fertility timing, male factors matter too. Men should avoid hot tubs and saunas (heat damages sperm), limit alcohol, avoid smoking, and maintain a healthy lifestyle. If you've been trying for 12 months without success (or 6 months if you're over 35), both partners should be evaluated by a fertility specialist.
Using Lubricants That Harm Sperm
Many commercial lubricants can reduce sperm motility or even kill sperm. A study published in Fertility and Sterility found that common water-based lubricants significantly impaired sperm motility. If you need lubrication, look for "fertility-friendly" lubricants specifically designed not to harm sperm. Better yet, rely on your own fertile cervical mucus, which naturally lubricates and supports sperm.
Cumulative Conception Probability
One of the most common questions couples have when trying to conceive is: "How long will it take?" The answer depends on several factors, but research from the American Society for Reproductive Medicine (ASRM) gives us reliable data on cumulative conception rates over time. Understanding these probabilities can help set realistic expectations and reduce unnecessary anxiety during your conception journey.
The probability of conception on any single day within the fertile window varies significantly depending on timing relative to ovulation. According to a landmark study by Wilcox et al., published in the New England Journal of Medicine, the highest single-day conception probability is approximately 33% on the day before ovulation (O-1). As noted by Johns Hopkins Medicine, this probability window is narrower than many couples expect.
| Day Relative to Ovulation | Single-Act Conception Rate | Cumulative If Trying Daily | Sperm Viability |
|---|---|---|---|
| O-5 (5 days before) | ~10% | 10% | Low -- sperm nearing end of lifespan |
| O-4 (4 days before) | ~16% | 24% | Moderate -- older sperm present |
| O-3 (3 days before) | ~14% | 35% | Good -- sperm still viable |
| O-2 (2 days before) | ~27% | 52% | High -- optimal sperm age |
| O-1 (1 day before) | ~33% | 68% | Peak -- fresh sperm waiting for egg |
| O (ovulation day) | ~8% | 70% | Declining -- egg aging rapidly |
| O+1 (1 day after) | ~0% | 70% | None -- egg no longer viable |
Over multiple cycles, the cumulative probability of conception increases substantially. According to data compiled by Healthline, approximately 80% of healthy couples under 35 conceive within 6 months of timed intercourse, and about 90% within 12 months. These numbers assume that the couple is timing intercourse within the fertile window and that there are no underlying fertility issues. Tracking ovulation signs and using ovulation predictor kits can help you identify the two or three most productive days each cycle.
Male Factors That Affect the Fertile Window
While much of the discussion about the fertile window centers on female biology -- ovulation timing, cervical mucus, and egg viability -- the male partner's reproductive health plays an equally critical role in whether conception actually occurs. According to WebMD, male factor issues contribute to approximately 40-50% of all infertility cases. Even when ovulation timing is perfect, suboptimal sperm quality can significantly reduce the chances of fertilization.
Sperm health is measured across several parameters: count (total number), motility (ability to swim), morphology (shape), and vitality (percentage alive). Each of these can be influenced by lifestyle factors, many of which are modifiable. A comprehensive fertility tracking approach should include attention to male factors alongside female cycle monitoring. The ASRM recommends that both partners optimize their health when trying to conceive.
| Factor | Impact on Sperm | Recommendation | Recovery Time |
|---|---|---|---|
| Heat exposure | Reduces count and motility; damages DNA | Avoid hot tubs, saunas, laptop on lap; wear loose underwear | 2-3 months (full spermatogenesis cycle) |
| Smoking | Decreases count by 13-17%; impairs morphology | Quit smoking completely; avoid secondhand smoke | 3 months after cessation |
| Alcohol | Heavy use lowers testosterone, count, and motility | Limit to 1-2 drinks per day maximum; ideally reduce further | 2-3 months after reducing intake |
| Obesity (BMI > 30) | Hormonal disruption; increased scrotal temperature; DNA damage | Achieve healthy weight through diet and exercise | 3-6 months with sustained weight loss |
| Medications | Some SSRIs, testosterone, anabolic steroids impair sperm | Review all medications with a doctor before TTC | Varies by medication (weeks to months) |
| Abstinence period | Too long (>5 days): increased DNA damage. Too short: lower volume | Ejaculate every 2-3 days during the fertile window | Immediate improvement with correct frequency |
| Stress | Elevated cortisol suppresses testosterone and sperm production | Practice stress management; adequate sleep (7-9 hours) | Weeks to months depending on severity |
| Diet and supplements | Antioxidant deficiency linked to lower motility and DNA integrity | Eat zinc, selenium, folate, CoQ10; consider a male fertility supplement | 2-3 months for measurable improvement |
Because sperm take approximately 74 days (about 2.5 months) to fully develop, lifestyle changes made today will affect sperm quality roughly 3 months from now. This means couples should ideally begin optimizing male health at least 3 months before they begin timing intercourse to their fertile window. If the male partner has known risk factors or if the couple has been trying for more than 6-12 months, a semen analysis is a straightforward and valuable first diagnostic step.
Fertile Window Myths Debunked
Misinformation about fertility and the fertile window is widespread, and some persistent myths can actually reduce your chances of conceiving. Below, we address three of the most common misconceptions using evidence from the Johns Hopkins Medicine fertility resources and peer-reviewed research. Understanding the facts can help you avoid wasting precious cycles on strategies that do not work -- and focus on those that do.
Debunking these myths is not just academic -- acting on false information can genuinely cost you months of missed opportunities. If you are concerned about irregular periods or have been trying without success, our guide on when to see a fertility specialist can help you decide when professional guidance is warranted.
Related Reading
Explore all of our in-depth guides on ovulation, fertility, and reproductive health:
- Ovulation Calculator -- Free tool to predict your fertile window and ovulation date
- About Ovulation Calculator -- Learn about our mission and methodology
- Signs of Ovulation: How to Know When You're Fertile
- The Menstrual Cycle and Ovulation Explained
- Due Date Calculator Based on Ovulation Date
- How Many Days After Your Period Do You Ovulate?
- Basal Body Temperature and Ovulation
- Cervical Mucus and Fertility
- OPK Ovulation Predictor Kits
- Irregular Periods and Ovulation
- Ovulation With Irregular Periods
- The Four Phases of Your Menstrual Cycle Explained
- How Long After Ovulation Is Your Period?
- Due Date Calculation Methods Compared
- Clearblue Ovulation Calculator Guide
- Best Fertility Tracker Apps
- When to See a Fertility Specialist
Find Your Fertile Window
Use our free ovulation calculator to identify your most fertile days and maximize your chances of conception.
Calculate NowFrequently Asked Questions
Pregnancy can only occur when a viable egg meets viable sperm, which is only possible during the fertile window. However, because ovulation timing can vary from cycle to cycle, what seems like conception "outside" the fertile window may actually mean ovulation occurred earlier or later than expected. This is why calendar-based methods alone aren't reliable for birth control. For more on recognizing when ovulation is happening, read our guide to signs of ovulation.
Calendar-based predictions are accurate within a 2-3 day window for about 80% of women with regular cycles. OPKs are more precise, typically predicting ovulation within 24-36 hours. For maximum accuracy, combine multiple methods: calendar tracking, cervical mucus monitoring, and OPKs.
Before ovulation is significantly better. Because sperm can survive up to 5 days but eggs only 12-24 hours, having sperm already present when ovulation occurs gives the best conception chances. After ovulation, the egg quickly becomes non-viable. The ideal strategy is having intercourse in the 1-2 days before ovulation.
For men with normal sperm counts, daily intercourse does not significantly reduce fertility. Sperm concentration may be slightly lower with daily ejaculation, but there are still plenty for conception. In fact, abstaining for too long (more than 5-7 days) can actually decrease sperm quality due to increased DNA damage. Every 1-2 days is optimal.
Irregular cycles make it harder to predict ovulation with calendar methods alone. Focus on fertility signs like cervical mucus (fertile mucus indicates approaching ovulation) and use OPKs to detect your LH surge. Having intercourse every 2-3 days throughout the month ensures you cover your fertile window even when you can't predict exactly when it occurs. If cycles are very irregular, consult a healthcare provider.
No. Research from the American Society for Reproductive Medicine confirms that daily intercourse during the fertile window yields conception rates nearly identical to every-other-day intercourse (~37% vs. ~33% per cycle). While sperm concentration per ejaculation may be slightly lower with daily frequency, the total number of motile sperm remains more than sufficient for fertilization. The key is consistency during the fertile window rather than frequency alone. For men with known low sperm counts, every-other-day may be slightly preferable.
Age does not significantly change when the fertile window occurs within a cycle, but it profoundly affects the probability of conception during that window. According to ACOG, women under 30 have approximately a 25-30% chance of conceiving per fertile cycle, while women aged 35-39 have about a 15-20% chance, and women over 40 have roughly 5-10%. The primary age-related factor is egg quality (increased chromosomal abnormalities), not the fertile window timing itself. Ovarian reserve (the number of remaining eggs) also declines with age.
Yes, many commercial lubricants can significantly impair sperm motility and viability. Studies have shown that water-based lubricants like KY Jelly and Astroglide can reduce sperm motility by 60-100%. Even saliva has been shown to impair sperm function. If lubrication is needed during the fertile window, use fertility-friendly options such as Pre-Seed (which is FDA-cleared as fertility-compatible), canola oil, or mineral oil. These have been shown not to impair sperm function in laboratory studies.
The Sperm Meets Egg Plan is a structured approach to timed intercourse that combines calendar tracking with OPK testing. Starting on cycle day 8, couples have intercourse every other day. Once a positive OPK is detected, they have intercourse that day, the next day, skip a day, then once more. This method ensures good coverage of the fertile window while managing frequency for optimal sperm quality. Many couples find SMEP reduces the guesswork and stress of trying to time intercourse perfectly. See the intercourse frequency section above for the complete protocol.
For the most accurate results, wait until the day of your expected period or at least 12-14 days past ovulation (DPO). Testing too early can produce false negatives because hCG levels may not yet be detectable. Some sensitive tests can detect pregnancy as early as 10 DPO, but testing at 14 DPO with first morning urine provides the most reliable result. If you get a negative at 14 DPO, pregnancy from that cycle is very unlikely. For more about what happens after a positive test, see our due date calculator.
In fertile-quality cervical mucus (clear, stretchy, egg-white consistency), sperm can survive up to 5 days, with peak fertilization capacity lasting 2-3 days. In hostile or non-fertile mucus (thick, sticky, or absent), sperm typically die within hours. Fertile mucus provides nutrients, maintains a sperm-friendly pH of 7.0-8.5, and creates transport channels that guide sperm toward the uterus. For more on recognizing different mucus types, see our cervical mucus and fertility guide.
Saliva is not recommended as a lubricant when trying to conceive. Studies have shown that saliva can impair sperm motility by 20-30% due to its enzymatic content and hypotonic nature (it causes sperm to swell and potentially burst). If lubrication is needed, fertility-friendly lubricants such as Pre-Seed are specifically designed to mimic fertile cervical mucus and do not harm sperm. Coconut oil and mineral oil are also less harmful alternatives. See the lubricants and fertility section for a full comparison.
Implantation bleeding is light spotting that can occur when the fertilized egg attaches to the uterine lining. It typically happens between 6-12 days past ovulation (DPO), with the most common timing being 8-10 DPO. Not all women experience it -- estimates suggest only about 15-25% of pregnancies involve noticeable implantation bleeding. It is usually lighter in color (pink or light brown) and shorter in duration (1-2 days) than a regular period. The Cleveland Clinic has more information on distinguishing implantation bleeding from other causes of spotting.
While the Shettles method suggests that intercourse timing relative to ovulation can influence baby gender, current scientific evidence does not support this theory. A comprehensive review published in the British Medical Journal found no statistically significant relationship between intercourse timing and offspring sex. The sex of a baby is determined by whether the fertilizing sperm carries an X or Y chromosome, and there is no reliable natural method to influence this outcome through timing or frequency of intercourse.
Diet and exercise do not change when the fertile window occurs, but they can significantly affect whether conception succeeds during that window. A balanced diet rich in folate, zinc, and antioxidants supports egg and sperm quality. Moderate exercise improves blood flow to reproductive organs. However, excessive exercise (such as intense endurance training) can suppress ovulation by disrupting the hypothalamic-pituitary-ovarian axis. Being significantly underweight or overweight can also impair ovulation regularity. The ASRM recommends maintaining a healthy BMI (18.5-24.9) and eating a nutrient-rich diet when trying to conceive.
Yes. Research from Johns Hopkins and other institutions has shown that exposure to certain environmental chemicals -- including BPA (found in some plastics), phthalates (found in fragrances and plastics), pesticides, and heavy metals -- can impair both male and female fertility. These endocrine-disrupting chemicals can interfere with hormone signaling, reduce egg quality, lower sperm counts, and disrupt the timing of ovulation. To minimize exposure, consider using glass or stainless steel food containers, choosing fragrance-free personal care products, washing fruits and vegetables thoroughly, and filtering drinking water.
The gold standard for confirming ovulation at home is a sustained rise in basal body temperature (BBT). After ovulation, progesterone causes your BBT to rise by 0.3-0.5 degrees Fahrenheit and remain elevated throughout the luteal phase. A positive OPK predicts that ovulation is likely to occur within 24-36 hours, but it does not confirm that the egg was actually released -- in rare cases, an LH surge can occur without ovulation (called luteinized unruptured follicle syndrome). Combining OPKs with BBT tracking provides both advance warning and retrospective confirmation. A progesterone blood test on cycle day 21 can also confirm ovulation medically.
Medical Disclaimer
This article is for informational purposes only and should not replace medical advice. If you've been trying to conceive for 12 months without success (or 6 months if you're over 35), consult a healthcare provider or fertility specialist. Individual factors can significantly affect fertility, and this general information may not apply to your specific situation.
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